Article
Killer cell immunoglobulin-like receptor genes in Spanish multiple sclerosis patients.
Molecular immunology - 1 Sept 2011
García-León Juan A, Pinto-Medel María J, García-Trujillo Lucía, López-Gómez Carlos, Oliver-Martos Begoña, Prat-Arrojo Isidro, Marín-Bañasco Carmen, Suardíaz-García Margarita, Maldonado-Sanchez Rafael, Fernández-Fernández Oscar, Leyva-Fernández Laura
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIRs) are regulators of cytolytic activity of natural killer and certain T cells through interactions with human leukocyte antigen (HLA) class I ligands. KIRs have been shown to contribute to the pathogenesis of several autoimmune diseases, but their role in multiple sclerosis (MS) is still unclear. Here we determined the influence of KIR genes and their HLA class I...
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