Article
Hepatitis B virus drug resistance tools: one sequence, two predictions.
Intervirology - 1 Jan 2014
Neumann-Fraune Maria, Beggel Bastian, Kaiser Rolf, Obermeier Martin
Abstract excerpt
Drug resistance testing, genotype analysis, and the determination of immune and vaccine escape variants support personalized antiviral treatment for hepatitis B patients. As phenotypic drug resistance testing for hepatitis B virus (HBV) is especially labor-intensive, due to the lack of simple cell culture systems, genotypic methods play a very pronounced role. The genetic structure of HBV allows the simultaneous...
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