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Article

Molecular diagnosis and treatment of drug-resistant hepatitis B virus.

World journal of gastroenterology - 21 May 2014

Kim Jeong Han, Park Yong Kwang, Park Eun-Sook, Kim Kyun-Hwan

Abstract excerpt

Oral antiviral agents have been developed in the last two decades for the treatment of chronic hepatitis B (CHB). However, antiviral resistance remains an important challenge for long-term CHB therapy. All of the clinically available oral antiviral agents are nucleoside or nucleotide analogues that target the activity of viral reverse transcriptase (RT), and all are reported to have resistant mutations. Since the...

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Identifiers

PMID: 24914332
DOI: 10.3748/wjg.v20.i19.5708
PMCID: PMC4024781

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