Article
Genotyping hepatitis B virus dual infections using population-based sequence data.
The Journal of general virology - 1 Sept 2012
Beggel Bastian, Neumann-Fraune Maria, Döring Matthias, Lawyer Glenn, Kaiser Rolf, Verheyen Jens, Lengauer Thomas
Abstract excerpt
The hepatitis B virus (HBV) is classified into distinct genotypes A-H that are characterized by different progression of hepatitis B and sensitivity to interferon treatment. Previous computational genotyping methods are not robust enough regarding HBV dual infections with different genotypes. The correct classification of HBV sequences into the present genotypes is impaired due to multiple ambiguous sequence...
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