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Article

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents.

PloS one - 1 Jan 2016

Kalaghatgi Prabhav, Sikorski Anna Maria, Knops Elena, Rupp Daniel, Sierra Saleta, Heger Eva, Neumann-Fraune Maria, Beggel Bastian, Walker Andreas, Timm Jörg, Walter Hauke, Obermeier Martin, Kaiser Rolf, Bartenschlager Ralf, Lengauer Thomas

Abstract excerpt

The face of hepatitis C virus (HCV) therapy is changing dramatically. Direct-acting antiviral agents (DAAs) specifically targeting HCV proteins have been developed and entered clinical practice in 2011. However, despite high sustained viral response (SVR) rates of more than 90%, a fraction of patients do not eliminate the virus and in these cases treatment failure has been associated with the selection of drug...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27196673
DOI: 10.1371/journal.pone.0155869
PMCID: PMC4873220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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