Hepatitis B immune escape and drug resistance mutations among blood donors in Gabon during the year 2022.

doi:10.1038/s41598-026-35616-0

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Hepatitis B immune escape and drug resistance mutations among blood donors in Gabon during the year 2022.

Scientific reports - 13 Jan 2026

Maulot-Bangola Denis, Fokam Joseph, Ngoufack Jagni Semengue Ezechiel, Svicher Valentina, Salpini Romina, Takou Désiré, Beloumou Grace Angong, Etame Naomi-Karell, Mangala Christian, Djupsa Ndjeyep Sandrine Claire, Wamba Anges Gar, Sosso Samuel Martin, Chenwi Collins Ambe, Nka Alex Durand, Tchouaket Tommo Michel Carlos, Fainguem Nadine, Kamgaing Rachel, Moor Vicky Ama, Gonsu Hortense Kamga, Ekane Gregory-Edie Halle, Awoh Rogers Ajeh, Tayou Claude, Mbanya Dora, Zoung-Kanyi Bissek Anne-Cecile, Penlap Veronique, Pellegrin Olivier Rebienot, Nkoa Thérèse, Colizzi Vittorio, Ndembi Nicaise, Perno Carlo-Federico, Ndjolo Alexis

Abstract excerpt

Hepatitis B virus (HBV) and specifically occult HBV infection (OBI) remains concerning in transfusion medicine in many countries. This study aimed to determine the burden of overt and occult HBV infections and characterize the circulating viral genotypes among blood donors in Gabon. A facility-based study was conducted among blood donors at the Gabon National Blood Transfusion Centre in 2022. Screening for HBsAg...

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Identifiers

PMID: 41530434
DOI: 10.1038/s41598-026-35616-0
PMCID: PMC12881341

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