Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis B virus escape mutants induced by antiviral therapy.

The Journal of antimicrobial chemotherapy - 1 Apr 2008

Sheldon Julie, Soriano Vincent

Abstract excerpt

The hepatitis B virus (HBV) polymerase and envelope genes overlap in such a way that resistance mutations to antiviral agents in the reverse transcriptase gene may affect the antigenicity of the HBV surface antigen. Mutant viruses may escape serological diagnosis using specific anti-HBV surface antigen antibodies, causing occult forms of chronic hepatitis B. Moreover, these HBV strains may evade vaccine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Viral
Share to Antiviral Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B virus

Share to Mutation

Source

Identifiers

PMID: 18218641
DOI: 10.1093/jac/dkn014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis B virus escape mutants induced by antiviral therapy.PMID 18218641Read ↗

Hepatitis B virus mutations associated with antiviral therapy.Semantic proximity Read ↗

Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until NowSemantic proximity Read ↗

Molecular virology of hepatitis B virus.Semantic proximity Read ↗

Human hepatitis B virus mutants: significance of molecular changes.Semantic proximity Read ↗

Molecular genesis of drug-resistant and vaccine-escape HBV mutants.Semantic proximity Read ↗

Clinical implications of hepatitis B virus mutations: recent advances.Semantic proximity Read ↗

Hepatitis B antiviral resistance and vaccine escape: two sides of the same coin.Semantic proximity Read ↗

[Hepatitis B virus mutants--clinical significance].Semantic proximity Read ↗

Entecavir-resistant hepatitis B virus decreases surface antigenicity: A full genome and functional characterization.Semantic proximity Read ↗

Acute hepatitis B due to immune-escape mutations in a naturally immune patient.Semantic proximity Read ↗

The concept of hepatitis B virus mutant escape.Semantic proximity Read ↗

Hepatitis B vaccine: prophylactic, therapeutic, and diagnostic dilemma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.