Role of aberrant protein modification, assembly, and localization in cloned embryo phenotypes.

Abstract excerpt

Aberrant post-translational modifications of proteins contribute markedly to the abnormal characteristics of cloned embryos. This review summarizes aberrant aspects of protein modifications and protein interactions, taking an inside-outside view to the cell. These aberrant aspects affect a range of processes including the control of chromatin structure, expression of pluripotency genes, propagation of epigenetic...

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