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Article

Parental age and gene expression profiles in individual human blastocysts

30 Jan 2018

Abstract excerpt

The epigenetic status of the genome changes dynamically from fertilization to implantation. In addition, the physiological environment during the process of gametogenesis, including parental age, may affect the epigenome of the embryo after fertilization. It is important to clarify the influence of parental age on gene expression in the embryo in terms of transgenerational epigenetics to improve the techniques...

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Share to Epigenetics and DNA Methylation
Share to Prenatal Screening and Diagnostics
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PMID: 29402920
DOI: 10.1038/s41598-018-20614-8

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