Article
Echoes of the embryo: using the developmental biology toolkit to study cancer.
Disease models & mechanisms - 1 Feb 2016
Aiello Nicole M, Stanger Ben Z
Abstract excerpt
The hallmark of embryonic development is regulation - the tendency for cells to find their way into organized and 'well behaved' structures - whereas cancer is characterized by dysregulation and disorder. At face value, cancer biology and developmental biology would thus seem to have little to do with each other. But if one looks beneath the surface, embryos and cancers share a number of cellular and molecular...
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