Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tough beginnings: alterations in the transcriptome of cloned embryos during the first two cell cycles.

Developmental biology - 1 Apr 2007

Vassena Rita, Han Zhiming, Gao Shaorong, Baldwin Donald A, Schultz Richard M, Latham Keith E

Abstract excerpt

Cloned embryos produced by somatic cell nuclear transfer (SCNT) display a plethora of phenotypic characteristics that make them different from fertilized embryos, indicating defects in the process of nuclear reprogramming by the recipient ooplasm. To elucidate the extent and timing of nuclear reprogramming, we used microarrays to analyze the transcriptome of mouse SCNT embryos during the first two cell cycles. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Reprogramming
Share to Cloning, Organism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Developmental

Share to Nuclear Transfer Techniques

Share to Oligonucleotide Array Sequence Analysis

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 17234177
DOI: 10.1016/j.ydbio.2006.12.015
PMCID: PMC1868510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tough beginnings: alterations in the transcriptome of cloned embryos during the first two cell cycles.PMID 17234177Read ↗

Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencingSemantic proximity Read ↗

Somatic Cell Nuclear Transfer Embryos Show Massive Dysregulation of Genes Involved in Transcription PathwaysSemantic proximity Read ↗

Transcriptional reprogramming of gene expression in bovine somatic cell chromatin transfer embryosSemantic proximity Read ↗

Characterization of transcriptional activity during ZGA in mammalian SCNT embryoSemantic proximity Read ↗

Abnormal gene expression in regular and aggregated somatic cell nuclear transfer placentasSemantic proximity Read ↗

Reprogrammed Transcriptome in Rhesus-Bovine Interspecies Somatic Cell Nuclear Transfer EmbryosSemantic proximity Read ↗

Somatic cell-like features of cloned mouse embryos prepared with cultured myoblast nuclei.Semantic proximity Read ↗

Aberrant gene expression patterns in placentomes are associated with phenotypically normal and abnormal cattle cloned by somatic cell nuclear transfer.Semantic proximity Read ↗

Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencingSemantic proximity Read ↗

Reshaping the transcriptional frontier: Epigenetics and somatic cell nuclear transferSemantic proximity Read ↗

Massive dysregulation of genes involved in cell signaling and placental development in cloned cattle conceptus and maternal endometriumSemantic proximity Read ↗

Identification of Inappropriately Reprogrammed Genes by Large-Scale Transcriptome Analysis of Individual Cloned Mouse BlastocystsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.