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Article

The subcortical maternal complex: emerging roles and novel perspectives.

Molecular human reproduction - 1 Jul 2021

Bebbere Daniela, Albertini David F, Coticchio Giovanni, Borini Andrea, Ledda Sergio

Abstract excerpt

Since its recent discovery, the subcortical maternal complex (SCMC) is emerging as a maternally inherited and crucial biological structure for the initial stages of embryogenesis in mammals. Uniquely expressed in oocytes and preimplantation embryos, where it localizes to the cell subcortex, this multiprotein complex is essential for early embryo development in the mouse and is functionally conserved across...

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PMID: 34191027
DOI: 10.1093/molehr/gaab043

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