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Article

Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese.

American journal of human genetics - 3 May 2018

Wang Dong, Fan Yu, Malhi Mahadev, Bi Rui, Wu Yong, Xu Min, Yu Xiu-Feng, Long Heng, Li Yu-Ye, Zhang Deng-Feng, Yao Yong-Gang

Abstract excerpt

Genome-wide association studies (GWASs) and genome-wide linkage studies (GWLSs) have identified numerous risk genes affecting the susceptibility to leprosy. However, most of the reported GWAS hits are noncoding variants and account for only part of the estimated heritability for this disease. In order to identify additional risk genes and map the potentially functional variants within the GWAS loci, we performed...

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Source

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Identifiers

PMID: 29706348
DOI: 10.1016/j.ajhg.2018.03.006
PMCID: PMC5986702

Genes

LACC1

Variants

rs142179458
rs3764147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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