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Article

Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo.

Blood - 9 Oct 2014

Iqbal Asif J, McNeill Eileen, Kapellos Theodore S, Regan-Komito Daniel, Norman Sophie, Burd Sarah, Smart Nicola, Machemer Daniel E W, Stylianou Elena, McShane Helen, Channon Keith M, Chawla Ajay, Greaves David R

Abstract excerpt

The recruitment of monocytes and their differentiation into macrophages at sites of inflammation are key events in determining the outcome of the inflammatory response and initiating the return to tissue homeostasis. To study monocyte trafficking and macrophage differentiation in vivo, we have generated a novel transgenic reporter mouse expressing a green fluorescent protein (GFP) under the control of the human...

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Identifiers

PMID: 25030063
DOI: 10.1182/blood-2014-04-568691
PMCID: PMC4192756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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