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A <i>Csf1r</i>-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep

13 Aug 2016

Abstract excerpt

Expression of Csf1r in adults is restricted to cells of the macrophage lineage. Transgenic reporters based upon the Csf1r locus require inclusion of the highly conserved Fms-intronic regulatory element for expression. We have created Csf1r-EGFP transgenic sheep via lentiviral transgenesis of a construct containing elements of the mouse Fms-intronic regulatory element and Csf1r promoter. Committed bone marrow...

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PMID: 27521343
DOI: 10.4049/jimmunol.1502336

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