Article

Human macrophages survive and adopt activated genotypes in living zebrafish

2017-08-28

Abstract excerpt

The inflammatory response, modulated both by tissue resident macrophages and recruited monocytes from peripheral blood, plays a critical role in human diseases such as cancer and neurodegenerative disorders. Here, we sought a model to interrogate human immune behavior in vivo . We determined that primary human monocytes and macrophages survive in zebrafish for up to two weeks. Flow cytometry revealed that human m...

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Literature Corpus work: d6e7ac38-77a3-5072-9eda-2f7a1ab74d87
DOI: 10.1101/181685

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