Article
Discrepant Phenotyping of Monocytes Based on CX3CR1 and CCR2 Using Fluorescent Reporters and Antibodies.
Cells - 10 May 2024
Sommer Katrin, Garibagaoglu Hilal, Paap Eva-Maria, Wiendl Maximilian, Müller Tanja M, Atreya Imke, Krönke Gerhard, Neurath Markus F, Zundler Sebastian
Abstract excerpt
Monocytes, as well as downstream macrophages and dendritic cells, are essential players in the immune system, fulfilling key roles in homeostasis as well as in inflammatory conditions. Conventionally, driven by studies on reporter models, mouse monocytes are categorized into a classical and a non-classical subset based on their inversely correlated surface expression of Ly6C/CCR2 and CX3CR1. Here, we aimed to...
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