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Article

Distinct human and mouse membrane trafficking systems for sweet taste receptors T1r2 and T1r3.

PloS one - 1 Jan 2014

Shimizu Madoka, Goto Masao, Kawai Takayuki, Yamashita Atsuko, Kusakabe Yuko

Abstract excerpt

The sweet taste receptors T1r2 and T1r3 are included in the T1r taste receptor family that belongs to class C of the G protein-coupled receptors. Heterodimerization of T1r2 and T1r3 is required for the perception of sweet substances, but little is known about the mechanisms underlying this heterodimerization, including membrane trafficking. We developed tagged mouse T1r2 and T1r3, and human T1R2 and T1R3 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25029362
DOI: 10.1371/journal.pone.0100425
PMCID: PMC4100762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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