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Article

WNK4 regulates the secretory pathway via which TRPV5 is targeted to the plasma membrane.

Biochemical and biophysical research communications - 17 Oct 2008

Jiang Yi, Cong Peilong, Williams Shawn R, Zhang Wei, Na Tao, Ma He-Ping, Peng Ji-Bin

Abstract excerpt

TRPV5 and TRPV6 are two closely related epithelial calcium channels that mediate apical calcium entry in the transcellular calcium transport pathway. TRPV5, but not TRPV6, is enhanced by protein kinase WNK4 when expressed in Xenopus laevis oocytes. We report that the majority of human TRPV5 exogenously expressed in the Xenopus oocyte plasma membrane was complexly N-glycosylated whereas that for human TRPV6 was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18703016
DOI: 10.1016/j.bbrc.2008.08.010
PMCID: PMC2570258

Genes

TRPV5
TRPV6
WNK4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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