Article
Polymorphisms in TLR1, TLR6 and TLR10 genes and the risk of Graves' disease.
Autoimmunity - 1 Feb 2015
Xiao WenJuan, Liu ZeLin, Lin JiangHai, Li JingBo, Wu KeJing, Ma Yun, Gong YingXue, Liu ZeHuan
Abstract excerpt
Graves' disease (GD) is postulated to be caused by the combined effects of susceptibility genes and environmental triggers. Toll-like receptors (TLRs) play a role in the activation of innate and adaptive immune responses in mammalians. The aim of this study was to evaluate the potential association of polymorphisms in TLR1, TLR6 and TLR10 genes with GD in Chinese Cantonese population. Seven single nucleotide...
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