Article
Association of Toll-like receptor 10 polymorphisms with autoimmune thyroid disease in Korean children.
Thyroid : official journal of the American Thyroid Association - 1 Feb 2015
Cho Won Kyoung, Jang Jung-Pil, Choi Eun-Jeong, Jeon Yeon Jin, Jung In Ah, Kim Shin-Hee, Jung Min Ho, Kim Tai-Gyu, Suh Byung-Kyu
Abstract excerpt
BACKGROUND: The Toll-like receptors (TLRs) are germline-encoded receptors that play an essential role in initiating the immune response against pathogens. In this study, we assess the association of TLR polymorphism with autoimmune thyroid disease (AITD) in Korean children. METHODS: We investigated three polymorphisms in the TLR10 gene (rs4129009, rs11096956, and rs10004195) in 85 Korean AITD patients (Graves'...
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