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Article

Polymorphisms and expression of toll-like receptors in autoimmune thyroid diseases.

Autoimmunity - 1 May 2017

Inoue Naoya, Katsumata Yuka, Watanabe Mikio, Ishido Naoko, Manabe Yu, Watanabe Ayano, Masutani Ryota, Hidaka Yoh, Iwatani Yoshinori

Abstract excerpt

Graves' disease (GD) and Hashimoto's disease (HD) are autoimmune thyroid diseases (AITDs). Prognosis of AITDs varies in each patient. Toll-like receptors (TLRs) are pattern-recognition receptors that activate signaling pathways involved in the production of proinflammatory cytokines. UNC93B1 is a transcription factor of TLR7 and TLR9. In this study, we examined the association of TLR expression and TLR and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28013570
DOI: 10.1080/08916934.2016.1261835

Genes

TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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