Article
Pharmacokinetic profile of dextromethorphan hydrobromide in a syrup formulation in children and adolescents.
Clinical drug investigation - 1 Sept 2014
Guenin Eric, Armogida Marianna, Riff Dennis
Abstract excerpt
BACKGROUND: Dextromethorphan hydrobromide (DM) is a widely used antitussive. This study determined, for the first time, the basic pharmacokinetic profile of DM and its active metabolite, dextrorphan (DP) in children and adolescents. METHODS: Thirty-eight male and female subjects at risk for developing an upper respiratory tract infection (URTI), or symptomatic with cough due to URTI, were enrolled in this...
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