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Article

Effect of Apoptotic Cell Recognition on Macrophage Polarization and Mycobacterial Persistence

15 Jul 2014

Abstract excerpt

Intracellular Mycobacterium leprae infection modifies host macrophage programming, creating a protective niche for bacterial survival. The milieu regulating cellular apoptosis in the tissue plays an important role in defining susceptible and/or resistant phenotypes. A higher density of apoptotic cells has been demonstrated in paucibacillary leprosy lesions than in multibacillary ones. However, the effect of...

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PMID: 25024361
DOI: 10.1128/iai.02194-14

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