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Efferocytosis of Pathogen-Infected Cells

22 Dec 2017

Abstract excerpt

The prompt and efficient clearance of unwanted and abnormal cells by phagocytes is termed efferocytosis, and is crucial for organism development, the maintenance of tissue homeostasis, and regulation of the immune system. Dying cells are recognized by phagocytes through pathways initiated via “find-me” signals, recognition via “eat-me” signals and down-modulation of regulatory “don’t eat-me” signals. Pathogen...

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PMID: 29312342
DOI: 10.3389/fimmu.2017.01863

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