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Macrophage Apoptosis in Tuberculosis

1 Jan 2009

Abstract excerpt

Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that infects alveolar macrophages following aerosol transmission. Lung macrophages provide a critical intracellular niche that is required for Mtb to establish infection in the human host. This parasitic relationship is made possible by the capacity of Mtb to block phagosome maturation following entry into the host macrophage, creating an environment...

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PMID: 19259342
DOI: 10.3349/ymj.2009.50.1.1

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