Polymorphism of DEFA in Chinese Han population with IgA nephropathy.

doi:10.1007/s00439-014-1464-y

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Polymorphism of DEFA in Chinese Han population with IgA nephropathy.

Human genetics - 1 Oct 2014

Xu Ricong, Feng Shaozhen, Li Zhijian, Fu Yonggui, Yin Peiran, Ai Zhen, Liu Wenting, Yu Xueqing, Li Ming

Abstract excerpt

Our recent genome-wide association study (GWAS) had discovered a new locus at 8p23 (rs2738048) associated with IgA nephropathy (IgAN) in Chinese Han patients, implicating the DEFA gene family within this locus as susceptibility genes. However, it is still unknown whether there are additional variations within these genes associated with the disease susceptibility. The aim of this study is to investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glomerulonephritis, IGA

Share to alpha-Defensins

Share to Asian People

Share to Case-Control Studies

Share to HEK293 Cells

Share to Linkage Disequilibrium

Share to Multigene Family

Source

Open in PubMed

Identifiers

PMID: 25024040
DOI: 10.1007/s00439-014-1464-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of DEFA in Chinese Han population with IgA nephropathy.PMID 25024040Read ↗

DEFA gene variants associated with IgA nephropathy in a Chinese population.Semantic proximity Read ↗

A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.Semantic proximity Read ↗

Identification of new susceptibility loci for IgA nephropathy in Han Chinese.Semantic proximity Read ↗

3' untranslated region variants in DEFA5 gene associated with susceptibility to IgA nephropathy in the Chinese Han population.Semantic proximity Read ↗

Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy.Semantic proximity Read ↗

Association between CCDC132, FDX1 and TNFSF13 gene polymorphisms and the risk of IgA nephropathy.Semantic proximity Read ↗

Genetic polymorphisms in TNFSF13 and FDX1 are associated with IgA nephropathy in the Han Chinese population.Semantic proximity Read ↗

Low α-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction.Semantic proximity Read ↗

Exome Chip Analyses and Genetic Risk for IgA Nephropathy among Han Chinese.Semantic proximity Read ↗

Identification of susceptibility loci and relevant cell type for IgA nephropathy in Han Chinese by integrative genome-wide analysis.Semantic proximity Read ↗

A Functional Variant rs3093023 in CCR6 Is Associated With IgA Nephropathy by Regulating Th17 Cells in a North Han Chinese Population.Semantic proximity Read ↗

Genetic variants of the MIR31HG gene are related to a risk of IgA nephropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.