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Article

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication.

Virology journal - 14 Jul 2014

Tynell Janne, Melén Krister, Julkunen Ilkka

Abstract excerpt

BACKGROUND: The influenza A virus NS1 protein is a virulence factor and an antagonist of host cell innate immune responses. During virus infection NS1 protein has several functions both in the nucleus and in the cytoplasm and its intracellular localization is regulated by one or two nuclear localization signals (NLS) and a nuclear export signal (NES). METHODS: In order to investigate the role of NS1 NES in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25023993
DOI: 10.1186/1743-422X-11-128
PMCID: PMC4112715

Genes

NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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