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Article

Identification and characterization of three novel nuclear export signals in the influenza A virus nucleoprotein.

Journal of virology - 1 May 2012

Yu Maorong, Liu Xiaoling, Cao Shuai, Zhao Zhendong, Zhang Ke, Xie Qing, Chen Caiwei, Gao Shengyan, Bi Yuhai, Sun Lei, Ye Xin, Gao George F, Liu Wenjun

Abstract excerpt

The nuclear export of the influenza A virus ribonucleoprotein (vRNP) is crucial for virus replication. As a major component of the vRNP, nucleoprotein (NP) alone can also be shuttled out of the nucleus by interacting with chromosome region maintenance 1 (CRM1) and is therefore hypothesized to promote the nuclear export of the vRNP. In the present study, three novel nuclear export signals (NESs) of the NP--NES1,...

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Identifiers

PMID: 22345439
DOI: 10.1128/JVI.06159-11
PMCID: PMC3347336

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Source receipt: pubmed, retrieved 7 Sept 2026.

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