Article
Combined genetic and nutritional risk models of triple negative breast cancer.
Nutrition and cancer - 1 Jan 2014
Lee Eunkyung, Levine Edward A, Franco Vivian I, Allen Glenn O, Gong Feng, Zhang Yanbin, Hu Jennifer J
Abstract excerpt
Triple negative breast cancer (TNBC) presents clinical challenges due to unknown etiology, lack of treatment targets, and poor prognosis. We examined combined genetic and nutritional risk models of TNBC in 354 breast cancer cases. We evaluated 18 DNA-repair nonsynonymous single nucleotide polymorphisms (nsSNPs) and dietary/nutritional intakes. Multivariate Adaptive Regression Splines models were used to select...
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