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Article

Polymorphism in the Promoter Region of the IL18 Gene and the Association With Severity on Paracoccidioidomycosis

1 Oct 2020

Abstract excerpt

Paracoccidioidomycosis is an important endemic systemic disease in Latin America, caused by Paracoccidioides spp. This mycosis has been associated with high morbidity and sequels, and its clinical manifestations depend on the virulence of the infecting strain, the degree and type of immune response, infected tissues, and intrinsic characteristics of the host. The Th(T helper)1 and Th17/Th22 cells were related...

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PMID: 33117339
DOI: 10.3389/fimmu.2020.542210

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