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Article

Upregulation of regulator of G-protein signaling 2 in the sclera of a form deprivation myopic animal model.

Molecular vision - 1 Jan 2014

Zou Leilei, Liu Rui, Zhang Xiaohui, Chu Renyuan, Dai Jinhui, Zhou Hao, Liu Hong

Abstract excerpt

PURPOSE: Scleral remodeling is an important mechanism underlying the development of myopia. Atropine, an antagonist of G protein-coupled muscarinic receptors, is currently used as an off-label treatment for myopia. Regulator of G-protein signaling 2 (RGS2) functions as an intracellular selective inhibitor of muscarinic receptors. In this study we measured scleral RGS2 expression and scleral remodeling in an...

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Identifiers

PMID: 25018620
PMCID: PMC4087119

Genes

RGS2
PIGS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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