Article
The FGF2 gene in a myopia animal model and human subjects.
Molecular vision - 1 Jan 2012
An Jianhong, Hsi Edward, Zhou Xiangtian, Tao Yijin, Juo Suh-Hang Hank, Liang Chung-Ling
Abstract excerpt
PURPOSE: Fibroblast growth factor-2 (FGF2) has been implied in the development of myopia according to previous studies investigating FGF2 in the sclera and retinal pigment epithelium. This study measured retinal FGF2 gene expression in an animal model and also tested for the association between single nucleotide polymorphisms (SNPs) in FGF2 and high myopia. METHODS: The guinea pigs were assigned to 2 groups: form...
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