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Article

Genome-Wide Scleral Micro- and Messenger-RNA Regulation During Myopia Development in the Mouse

10 Nov 2016

Abstract excerpt

PURPOSE: MicroRNA (miRNAs) have been previously implicated in scleral remodeling in normal eye growth. They have the potential to be therapeutic targets for prevention/retardation of exaggerated eye growth in myopia by modulating scleral matrix remodeling. To explore this potential, genome-wide miRNA and messenger RNA (mRNA) scleral profiles in myopic and control eyes from mice were studied. METHODS: C57BL/6J...

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PMID: 27832275
DOI: 10.1167/iovs.16-19563

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