Article
Duffy blood system and G6PD genetic variants in vivax malaria patients from Manaus, Amazonas, Brazil.
Malaria journal - 8 May 2022
Ferreira Natália S, Mathias Jéssica Lorena S, Albuquerque Sérgio Roberto L, Almeida Anne Cristine G, Dantas Ana C, Anselmo Fernanda C, Lima Emerson S, Lacerda Marcus Vinicius G, Nogueira Paulo A, Ramasawmy Rajendranath, Gonçalves Marilda S, Moura Neto José P
Abstract excerpt
BACKGROUND: Over a third of the world's population is at risk of Plasmodium vivax-induced malaria. The unique aspect of the parasite's biology and interactions with the human host make it harder to control and eliminate the disease. Glucose-6-phosphate dehydrogenase (G6PD) deficiency and Duffy-negative blood groups are two red blood cell (RBC) variations that can confer protection against malaria. METHODS:...
Topics
- Brazil
- Duffy Blood-Group System
- Female
- Genotype
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Malaria, Vivax
- Male
- Plasmodium vivax