Article
Efficient replication of over 180 genetic associations with self-reported medical data.
PloS one - 1 Jan 2011
Tung Joyce Y, Do Chuong B, Hinds David A, Kiefer Amy K, Macpherson J Michael, Chowdry Arnab B, Francke Uta, Naughton Brian T, Mountain Joanna L, Wojcicki Anne, Eriksson Nicholas
Abstract excerpt
While the cost and speed of generating genomic data have come down dramatically in recent years, the slow pace of collecting medical data for large cohorts continues to hamper genetic research. Here we evaluate a novel online framework for obtaining large amounts of medical information from a recontactable cohort by assessing our ability to replicate genetic associations using these data. Using web-based...
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