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Article

MiR-143/145 deficiency attenuates the progression of atherosclerosis in Ldlr-/-mice.

Thrombosis and haemostasis - 1 Oct 2014

Sala Federica, Aranda Juan F, Rotllan Noemi, Ramírez Cristina M, Aryal Binod, Elia Leonardo, Condorelli Gianluigi, Catapano Alberico Luigi, Fernández-Hernando Carlos, Norata Giuseppe Danilo

Abstract excerpt

The miR-143/145 cluster regulates VSMC specific gene expression, thus controlling differentiation, plasticity and contractile function, and promoting the VSMC phenotypic switch from a contractile/non-proliferative to a migrating/proliferative state. More recently increased miR-145 expression was observed in human carotid atherosclerotic plaques from symptomatic patients. The goal of this study was to investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25008143
DOI: 10.1160/TH13-11-0905
PMCID: PMC4180777

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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