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Article

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury.

Genes & development - 15 Sept 2009

Xin Mei, Small Eric M, Sutherland Lillian B, Qi Xiaoxia, McAnally John, Plato Craig F, Richardson James A, Bassel-Duby Rhonda, Olson Eric N

Abstract excerpt

Vascular injury triggers dedifferentiation and cytoskeletal remodeling of smooth muscle cells (SMCs), culminating in vessel occlusion. Serum response factor (SRF) and its coactivator, myocardin, play a central role in the control of smooth muscle phenotypes by regulating the expression of cytoske...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

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Share to Myocytes, Cardiac

Share to Myocytes, Smooth Muscle

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Source

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Identifiers

PMID: 19720868
DOI: 10.1101/gad.1842409
PMCID: PMC2751981

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19720868-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury.PMID 19720868Read ↗

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