Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparative study of ultra-deep pyrosequencing and cloning to quantitatively analyze the viral quasispecies using hepatitis B virus infection as a model.

Antiviral research - 1 May 2013

Ramírez Clara, Gregori Josep, Buti Maria, Tabernero David, Camós Sílvia, Casillas Rosario, Quer Josep, Esteban Rafael, Homs Maria, Rodriguez-Frías Francisco

Abstract excerpt

In this study, the reliability and reproducibility of viral quasispecies quantification by three ultra-deep pyrosequencing (UDPS) methods (FLX+, FLX, and Junior) were investigated and results compared with the conventional cloning technique. Hepatitis B virus (HBV) infection was selected as the m...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B virus

Share to High-Throughput Nucleotide Sequencing

Share to Molecular Sequence Data

Share to Phylogeny

Share to Viral Proteins

Source

Identifiers

PMID: 23523552
DOI: 10.1016/j.antiviral.2013.03.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23523552-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparative study of ultra-deep pyrosequencing and cloning to quantitatively analyze the viral quasispecies using hepatitis B virus infection as a model.PMID 23523552Read ↗

Comparison of next-generation sequencing and clone-based sequencing in analysis of hepatitis B virus reverse transcriptase quasispecies heterogeneity.Semantic proximity Read ↗

Analysis of ultra-deep pyrosequencing and cloning based sequencing of the basic core promoter/precore/core region of hepatitis B virus using newly developed bioinformatics tools.Semantic proximity Read ↗

Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants.Semantic proximity Read ↗

Whole genome characterization of hepatitis B virus quasispecies with massively parallel pyrosequencing.Semantic proximity Read ↗

Ultra-deep pyrosequencing analysis of the hepatitis B virus preCore region and main catalytic motif of the viral polymerase in the same viral genome.Semantic proximity Read ↗

Use of massively parallel ultradeep pyrosequencing to characterize the genetic diversity of hepatitis B virus in drug-resistant and drug-naive patients and to detect minor variants in reverse transcriptase and hepatitis B S antigen.Semantic proximity Read ↗

Comparison of quasispecies diversity of HCV between chronic hepatitis c and hepatocellular carcinoma by Ultradeep pyrosequencing.Semantic proximity Read ↗

Ultra-Deep Sequencing Characterization of HCV Samples with Equivocal Typing Results Determined with a Commercial Assay.Semantic proximity Read ↗

Inference with viral quasispecies diversity indices: clonal and NGS approaches.Semantic proximity Read ↗

A comparative study on the characterization of hepatitis B virus quasispecies by clone-based sequencing and third-generation sequencing.Semantic proximity Read ↗

Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing.Semantic proximity Read ↗

A comparison of parallel pyrosequencing and sanger clone-based sequencing and its impact on the characterization of the genetic diversity of HIV-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.