Article
CR1 is potentially associated with rate of decline in sporadic Alzheimer's disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Oct 2014
Schmidt Christian, Wolff Martin, von Ahsen Nicolas, Lange Katharina, Friede Tim, Zerr Inga
Abstract excerpt
The objective of this study was to investigate potential associations of Alzheimer's disease risk single nucleotide polymorphisms (SNP) with disease progression. SNP in ACE, ApoE, BIN1, CLU, CR1, CST3, EXOC3L2, GWA14q32.13, IL8, LDLR, PICALM, and TNK1 were determined in 40 Alzheimer's disease patients who were observed for 2 to 3 years. Annual Mini Mental State Examination (MMSE) loss was used as the outcome...
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