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Article

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2014

Sherva Richard, Tripodis Yorghos, Bennett David A, Chibnik Lori B, Crane Paul K, de Jager Philip L, Farrer Lindsay A, Saykin Andrew J, Shulman Joshua M, Naj Adam, Green Robert C

Abstract excerpt

BACKGROUND: Substantial interindividual variability exists in the disease trajectories of Alzheimer's disease (AD) patients. Some decline rapidly whereas others decline slowly, and there are no known explanations for this variability. We describe the first genome-wide association study to examine rate of cognitive decline in a sample of AD patients with longitudinal measures of cognition. METHODS: The discovery...

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Source

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Identifiers

PMID: 23535033
DOI: 10.1016/j.jalz.2013.01.008
PMCID: PMC3760995

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SPON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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