Article
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Shalaby Manal Ali, Nounou Howaida Attia, Ms Alanazi, O Alharby, Azzam Nahla, Saeed Hesham Mahmoud
Abstract excerpt
BACKGROUND: It has been reported that COX-2 expression is associated with MMP-2 expression in thyroid and breast cancers, suggesting that MMPs are linked to COX-2-mediated carcinogenesis. Several polymorphisms within the MMP2 promoter region have been reported in cases with oncogenesis and tumor progression, especially in colorectal carcinogenesis. MATERIALS AND METHODS: This research evaluated risk of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
