Article
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2009
Beeghly-Fadiel Alicia, Lu Wei, Long Ji-Rong, Shu Xiao-ou, Zheng Ying, Cai Qiuyin, Gao Yu-Tang, Zheng Wei
Abstract excerpt
Matrix metalloproteinase-2 (MMP-2) is a well-known mediator of cancer metastasis but is also thought to be involved in several aspects of cancer development, including cell growth and inflammation. We comprehensively characterized genetic variation across the MMP-2 gene and evaluated associations with breast cancer risk using a two-phase (phase 1 and phase 2) study design. A total of 39 polymorphisms were...
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