Article
Effect of variation of ABCB1 and ABCC3 genotypes on the survival of bone tumor cases after chemotherapy.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Yang Jie, Wang Zhi-Gang, Cai Hai-Qing, Li Yu-Chan, Xu Yun-Lan
Abstract excerpt
We conducted a comprehensive study to investigate the role of genes involved in transport pathways in response to chemotherapy and clinical outcome of osteosarcoma cases. Genotyping of six SNPs was performed in a 384-well plate format on the Sequenom MassARRAY platform for 208 osteosarcoma patients to reveal any correlations of the six SNPs with response to chemotherapy and clinical outcome. Individuals with the...
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