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Article

Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps.

Molecular cancer research : MCR - 1 Oct 2014

Sáenz Robles Maria Teresa, Chong Jean Leon, Koivisto Christopher, Trimboli Anthony, Liu Huayang, Leone Gustavo, Pipas James M

Abstract excerpt

UNLABELLED: Genetic and epigenetic events that alter gene expression and/or protein function or localization are thought to be the primary mechanism that drives tumorigenesis and governs the clinical behavior of cancers. Yet, a number of studies have shown that the effects of oncogene expression or tumor suppressor ablation are highly dependent on cell type. The molecular basis for this cell-type specificity and...

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Share to Adenomatous Polyps
Share to Antigens, Polyomavirus Transforming

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Intestines

Share to Oncogene Proteins, Viral

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Source

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Identifiers

PMID: 24994749
DOI: 10.1158/1541-7786.MCR-14-0166
PMCID: PMC4201981

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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