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Article

Therapeutic potential of semaphorin 3E for the treatment of choroidal neovascularization.

Investigative ophthalmology & visual science - 1 Jul 2014

Suda Kenji, Guo Congrong, Oishi Akio, Ikeda Shinya, Uemura Akiyoshi, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: We investigated the effects of semaphorin 3E (Sema3E)/PlexinD1 signaling in the development of choroidal neovascularization (CNV) and explored the therapeutic potential of the pathway. METHODS: We used a laser-induced CNV model in the mouse. The expression of Sema3E and PlexinD1 was evaluated with immunohistochemistry, real-time RT-PCR, and Western blotting. After the intravitreal injection of Sema3E,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24985470
DOI: 10.1167/iovs.14-14087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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