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Article

RORα modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis

23 Jun 2017

Abstract excerpt

ABSTRACT Pathological proliferation of retinal blood vessels commonly causes vision impairment in proliferative retinopathies, including retinopathy of prematurity. Dysregulated crosstalk between the vasculature and retinal neurons is increasingly recognized as a major factor contributing to the pathogenesis of vascular diseases. Class 3 semaphorins (SEMA3s), a group of neuron‐secreted axonal and vascular...

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PMID: 28646017
DOI: 10.1096/fj.201700172r

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