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Article

Target enzyme mutations confer differential echinocandin susceptibilities in Candida kefyr.

Antimicrobial agents and chemotherapy - 1 Sept 2014

Staab Janet F, Neofytos Dionysios, Rhee Peter, Jiménez-Ortigosa Cristina, Zhang Sean X, Perlin David S, Marr Kieren A

Abstract excerpt

Candida kefyr is an increasingly reported pathogen in patients with hematologic malignancies. We studied a series of bloodstream isolates that exhibited reduced echinocandin susceptibilities (RES). Clinical and surveillance isolates were tested for susceptibilities to all three echinocandins, and those isolates displaying RES to one or more echinocandins were selected for molecular and biochemical studies. The...

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Identifiers

PMID: 24982083
DOI: 10.1128/AAC.00096-14
PMCID: PMC4135851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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