A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A).

doi:10.1007/s00406-022-01447-z

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A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A).

European archives of psychiatry and clinical neuroscience - 1 Oct 2022

Guardiola-Ripoll Maria, Almodóvar-Payá Carmen, Lubeiro Alba, Sotero Alejandro, Salvador Raymond, Fuentes-Claramonte Paola, Salgado-Pineda Pilar, Papiol Sergi, Ortiz-Gil Jordi, Gomar Jesús J, Guerrero-Pedraza Amalia, Sarró Salvador, Maristany Teresa, Molina Vicente, Pomarol-Clotet Edith, Fatjó-Vilas Mar

Abstract excerpt

The CACNA1C and the ZNF804A genes are among the most relevant schizophrenia GWAS findings. Recent evidence shows that the interaction of these genes with the schizophrenia diagnosis modulates brain functional response to a verbal fluency task. To better understand how these genes might influence the risk for schizophrenia, we aimed to study the interplay between CACNA1C and ZNF804A on working memory brain...

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PMID: 35796825
DOI: 10.1007/s00406-022-01447-z

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