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Article

Genetic variants in SMARC genes are associated with DNA damage levels in Chinese population.

Toxicology letters - 2 Sept 2014

Gong Jianhang, Zhu Meng, Chu Minjie, Sun Chongqi, Chen Weihong, Jin Guangfu, Yuan Jing, Dai Juncheng, Wang Meilin, Pan Yun, Song Yuanchao, Ding Xiaojie, Du Mulong, Zhang Zhengdong, Hu Zhibin, Wu Tangchun, Shen Hongbing

Abstract excerpt

The switching defective/sucrose nonfermenting (SWI/SNF) related, matrix associated, actin dependent regulators of chromatin (SMARC) are components of human SWI/SNF like chromatin remodeling protein complexes, which are essential in the process of DNA damage repair. In this study, we hypothesized that genetic variants in SMARC genes may modify the capacity of DNA repair to damage. To test this hypothesis, we...

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Source

Identifiers

PMID: 24973491
DOI: 10.1016/j.toxlet.2014.06.034

Genes

SMARCA5
SMARCD2
SMARCD3
SMARCC2
SMARCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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